As a psychiatric and mental health
nurse practitioner, it is essential for you to have a strong background
in foundational neuroscience. In order to diagnose and treat patients,
you must not only understand the pathophysiology of psychiatric
disorders but also how medications for these disorders impact the
central nervous system. These concepts of foundational neuroscience can
be challenging to understand. Therefore, this Discussion is designed to
encourage you to think through these concepts, develop a rationale for
your thinking, and deepen your understanding by interacting with your
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For this Discussion, review the
Learning Resources and reflect on the concepts of foundational
neuroscience as they might apply to your role as the psychiatric mental
health nurse practitioner in prescribing medications for patients.
By Day 3 of Week 2
Post a response to each of the following:
Explain the agonist-to-antagonist spectrum of action of
psychopharmacologic agents, including how partial and inverse agonist
functionality may impact the efficacy of psychopharmacologic treatments.
Compare and contrast the actions of g couple proteins and ion gated channels.
Explain how the role of epigenetics may contribute to pharmacologic action.
Explain how this information may impact the way you prescribe
medications to patients. Include a specific example of a situation or
case with a patient in which the psychiatric mental health nurse
practitioner must be aware of the medication’s action.


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