Distinguish between the special sensory (taste) and general sensory nerve supply of the tongue Why is the colon referred to as the large intestine? The diameter of the colon is larger than that of the small intestine. The colon has the largest number of nerve endings in the digestive system. The colon absorbs the most nutrients. The colon is the longest portion of the gastrointestinal tract. The colon is the heaviest organ in the body.